Biología Estructural y Celular English version
Couto PM, Guardia CMA, Couto FL, Labriola CA, Labanda MS, Caramelo JJ. Acceptors stability modulates the efficiency of post-translational protein N-glycosylation. FASEB Journal. 2024 Jul 15;38(13):e23782. doi: https://doi.org/10.1096/fj.202302267r Pubmed
Abdian PL, Malori MS, Caramelo JJ, Checchi AM, Russo DM, Zorreguieta A, Berretta MF, Benintende G. Fusion of a bacterial cadherin-like domain and green fluorescent protein as a specific probe to study biofilm matrix formation in Rhizobium spp. Microbiology. 168(12):001284 (2022). doi:10.1099/mic.0.001284
Gonzalez Lopez Ledesma MM, Sanchez L, Ojeda DS, Oviedo Rouco S, Rossi AH, Varese A, Mazzitelli I, Pascuale CA, Miglietta EA, Rodríguez PE, Pallarés HM, Costa Navarro GS, Caramelo JJ, Rothlauf PW, Liu Z, Bloyet LM, Cornejo Pontelli M, Rasetto NB, Wenker SD, Ramis LY, Bialer MG, de Leone MJ, Hernando CE, Bianchimano L, Ríos AS, Treffinger Cienfuegos MS, Rodriguez García DR, Longueira Y, Laufer N, Alvarez D, Ceballos A, Ochoa V, Monzani C, Turk G, Salvatori M, Carradori J, Prost K, Rima A, Varela C, Ercole R, Toro RI, Gutierrez S, Zubieta M, Acuña D, Nabaes Jodar MS, Torres C, Mojsiejczuk L, Viegas M, Velazquez P, Testa C, Kreplak N, Yanovsky M, Whelan S, Geffner J, Pifano M, Gamarnik AV. Longitudinal Study after Sputnik V Vaccination Shows Durable SARS-CoV-2 Neutralizing Antibodies and Reduced Viral Variant Escape to Neutralization over Time. mBio. 13(1):e0344221 (2022). doi: 10.1128/mbio.03442-21. PubMed
Portales AE, Mustafá ER, McCarthy CI, Cornejo MP, Couto PM, Gironacci MM, Caramelo JJ, Perelló M, Raingo J. ACE2 internalization induced by a SARS-CoV-2 recombinant protein is modulated by angiotensin II type 1 and bradykinin 2 receptors. Life Sci. 293:120284 (2022). doi: 10.1016/j.lfs.2021.120284. PubMed
Bardeci NG, Tofolón E, Trajtenberg F, Caramelo J, Larrieux N, Rossi S, Buschiazzo A, Moreno S. The crystal structure of yeast regulatory subunit reveals key evolutionary insights into Protein Kinase A oligomerization. J Struct Biol. 213(2):107732 (2021). doi: 10.1016/j.jsb.2021.107732. PubMed
Honer J, Niemeyer KM, Fercher C, Diez Tissera AL, Jaberolansar N, Jafrani YMA, Zhou C, Caramelo JJ, Shewan AM, Schulz BL, Brodsky JL, Zacchi LF. TorsinA folding and N-linked glycosylation are sensitive to redox homeostasis. Biochim Biophys Acta Mol Cell Res. 1868(9):119073 (2021). doi: 10.1016/j.bbamcr.2021.119073. PubMed
Ojeda DS, Gonzalez Lopez Ledesma MM, Pallarés HM, Costa Navarro GS, Sanchez L, Perazzi B, Villordo SM, Alvarez DE; BioBanco Working Group, Echavarria M, Oguntuyo KY, Stevens CS, Lee B, Carradori J, Caramelo JJ, Yanovsky MJ, Gamarnik AV. Emergency response for evaluating SARS-CoV-2 immune status, seroprevalence and convalescent plasma in Argentina. PLoS Pathog. 17(1):e1009161 (2021). doi: 10.1371/journal.ppat.1009161. PubMed
Rossi AH, Ojeda DS, Varese A, Sanchez L, Gonzalez Lopez Ledesma MM, Mazzitelli I, Juliá AA, Rouco SO, Pallarés HM, Costa Navarro GS, Rasetto N, Garcia CI, Wenker SD, Ramis LY, Bialer MG, Jose de Leone M, Hernando CE, Sosa S, Bianchimano L, Rios A, Treffinger Cienfuegos MS, Caramelo JJ, Longueira Y, Laufer N, Alvarez D, Carradori J, Pedrozza D, Rima A, Echegoyen C, Ercole R, Gelpi P, Marchetti S, Zubieta M, Docena G, Kreplak N, Yanovsky M, Geffner J, Pifano M, Gamarnik AV. Sputnik V Vaccine Elicits Seroconversion and Neutralizing Capacity to SARS CoV-2 after a Single Dose. Cell Rep Med. 2(8):100359 (2021). doi: 10.1016/j.xcrm.2021.100359. PubMed
Simonovich VA, Burgos Pratx LD, Scibona P, Beruto MV, Vallone MG, Vázquez C, Savoy N, Giunta DH, Pérez LG, Sánchez MDL, Gamarnik AV, Ojeda DS, Santoro DM, Camino PJ, Antelo S, Rainero K, Vidiella GP, Miyazaki EA, Cornistein W, Trabadelo OA, Ross FM, Spotti M, Funtowicz G, Scordo WE, Losso MH, Ferniot I, Pardo PE, Rodriguez E, Rucci P, Pasquali J, Fuentes NA, Esperatti M, Speroni GA, Nannini EC, Matteaccio A, Michelangelo HG, Follmann D, Lane HC, Belloso WH. PlasmAr Study Group; COVIDAR Argentina Consortium: Gonzalez Lopez Ledesma MM, Sanchez LN, Costa Navarro GS, Pallares HM, Villordo SM, Alvarez DE, Caramelo JJ, Carradori J, Yanovsky MJ. A Randomized Trial of Convalescent Plasma in Covid-19 Severe Pneumonia. N Engl J Med. 384(7):619-629 (2021). doi: 10.1056/NEJMoa2031304. PubMed Clinical Trial
Giglio ML, Ituarte S, Milesi V, Dreon MS, Brola TR, Caramelo J, Ip JCH, Maté S, Qiu JW, Otero LH, Heras H. Exaptation of Two Ancient Immune Proteins Into a New Dimeric Pore-Forming Toxin in Snails. J Struct Biol. 211(2):107531 (2020). doi: 10.1016/j.jsb.2020.107531. PubMed
Couto P, Caramelo J (2019) “Glycoprotein Folding”. EN: Molecular Nutrition: Carbohydrates. 1st Edition (ed. Vinood Patel) Academic Press, pp. 60-68. ISBN 978-0-12-849886-6. Book chapter
Wetzler DE, Fuchs Wightman F, Bucci HA, Rinaldi J, Caramelo JJ, Iusem ND, Ricardi MM. Conformational plasticity of the intrinsically disordered protein ASR1 modulates its function as a drought stress-responsive gene. PLoS One. 13(8):e0202808 (2018). doi: 10.1371/journal.pone.0202808. PubMed
Angelani CR, Caramelo JJ, Curto LM, Delfino JM. Structural coalescence underlies the aggregation propensity of a β-barrel protein motif. PLoS One. 12(2):e0170607 (2017). doi: 10.1371/journal.pone.0170607. PubMed
Medus ML, Gomez GE, Zacchi LF, Couto PM, Labriola CA, Labanda MS, Bielsa RC, Clérico EM, Schulz BL, Caramelo JJ. N-glycosylation Triggers a Dual Selection Pressure in Eukaryotic Secretory Proteins. Sci Rep. 7(1):8788 (2017). doi: 10.1038/s41598-017-09173-6. PubMed
Fiszbein A, Giono LE, Quaglino A, Berardino BG, Sigaut L, von Bilderling C, Schor IE, Steinberg JH, Rossi M, Pietrasanta LI, Caramelo JJ, Srebrow A, Kornblihtt AR. Alternative Splicing of G9a Regulates Neuronal Differentiation. Cell Rep. 14: 2797-2808 (2016). doi: 10.1016/j.celrep.2016.02.063 PubMed