Terapias regenerativas y protectoras del Sistema Nervioso Central English version
Erhardt B, Frenkel L, Marcora MS, Farías MI, Ferrari CC, Pitossi FJ, Leal MC. Downregulation of Plasma Membrane Ca2+ ATPase driven by tyrosine hydroxylase-Gal4 reduces Drosophila lifespan independently of effects in neurons. Fly (Austin). 17(1):2192457 (2023). doi: 10.1080/19336934.2023.2192457. PubMed
Wenker SD, Farias MI, Gradaschi V, Garcia C, Beauquis J, Leal MC, Ferrari C, Zeng X, Pitossi FJ. Microglia-secreted TNF-α affects differentiation efficiency and viability of pluripotent stem cell-derived human dopaminergic precursors. PLoS One. 18(9):e0263021 (2023). doi: 10.1371/journal.pone.0263021. PubMed
Zaverucha-do-Valle C, Gubert F, Vasques JF, Mesentier-Louro L, Scemes E, Pitossi F, Santiago MF, Mendez-Otero R. Resident Neural Stem Cells. (2023) Resident Stem Cells and Regenerative Therapy: Sources and Clinical Applications, 2nd. Ed., pp. 127 - 157 doi: 10.1016/B978-0-443-15289-4.00014-7 Book Chapter
Silva BA, Farías MI, Miglietta EA, Leal MC, Ávalos JC, Pitossi FJ, Ferrari CC. Understanding the role of the blood brain barrier and peripheral inflammation on behavior and pathology on ongoing confined cortical lesions. Mult Scler Relat Disord. 57:103346 (2022). doi: 10.1016/j.msard.2021.103346. PubMed
Casalia ML, Casabona JC, García C, Cavaliere Candedo V, Quintá HR, Farías MI, Gonzalez J, Gonzalez Morón D, Córdoba M, Consalvo D, Mostoslavsky G, Urbano FJ, Pasquini J, Murer MG, Rela L, Kauffman MA, Pitossi FJ. A familiar study on self-limited childhood epilepsy patients using hIPSC-derived neurons shows a bias towards immaturity at the morphological, electrophysiological and gene expression levels. Stem Cell Res Ther. 2(1):590 (2021). doi: 10.1186/s13287-021-02658-2. PubMed
Erhardt B, Marcora MS, Frenkel L, Bochicchio PA, Bodin DH, Silva BA, Farías MI, Allo MÁ, Höcht C, Ferrari CC, Pitossi FJ, Leal MC. "Plasma Membrane Calcium ATPase downregulation in dopaminergic neurons alters cellular physiology and motor behavior in Drosophila melanogaster". Eur J Neurosci. 54(6):5915-5931 (2021). doi: 10.1111/ejn.15401. PubMed
Pitossi, FJ. The possible role of inflammation in the neurological sequelae of COVID-19 [El posible rol de la inflamación en las secuelas neurológicas del COVID-19]. Neurologia Argentina. 13(3):135-136 (2021). doi: 10.1016/j.neuarg.2021.09.001 Editorial
Silva BA, Leal MC, Farías MI, Erhardt B, Galeano P, Pitossi FJ, Ferrari CC. Environmental enrichment improves cognitive symptoms and pathological features in a focal model of cortical damage of Multiple Sclerosis. Brain Res. 1727:146520 (2020). doi: 10.1016/j.brainres.2019.146520. PubMed
Wenker SD, Pitossi FJ. Cell therapy for Parkinson's disease is coming of age: current challenges and future prospects with a focus on immunomodulation. Gene Ther. 27(1-2):6-14 (2020). doi: 10.1038/s41434-019-0077-4. PubMed Review
Galeano P, Leal MC, Ferrari CC, Dalmasso MC, Martino Adami PV, Farías MI, Casabona JC, Puntel M, Do Carmo S, Smal C, Arán M, Castaño EM, Pitossi FJ, Cuello AC, Morelli L. Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer. Mol Neurobiol. 55(11):8637-8650 (2018). doi: 10.1007/s12035-018-1002-3. PubMed
Rosato-Siri MV, Marziali L, Guitart ME, Badaracco ME, Puntel M, Pitossi F, Correale J, Pasquini JM. Iron Availability Compromises Not Only Oligodendrocytes But Also Astrocytes and Microglial Cells. Mol Neurobiol. 55(2):1068-1081 (2018). doi:10.1007/s12035-016-0369-2. PubMed
Silva BA, Leal MC, Farías MI, Avalos JC, Besada CH, Pitossi FJ, Ferrari CC. A new focal model resembling features of cortical pathology of the progressive forms of multiple sclerosis: Influence of innate immunity. Brain Behav Immun. 69:515-531 (2018). doi: 10.1016/j.bbi.2018.01.010. PubMed
Miraglia MC, Costa Franco MM, Rodriguez AM, Bellozi PM, Ferrari CC, Farias MI, Dennis VA, Barrionuevo P, de Oliveira AC, Pitossi F, Kim KS, Delpino MV, Oliveira SC, Giambartolomei GH. Glial Cell-Elicited Activation of Brain Microvasculature in Response to Brucella abortus Infection Requires ASC Inflammasome-Dependent IL-1β Production. J Immunol. 196 (9) 3794-3805 (2016). doi: 10.4049/jimmunol.1500908. PubMed
Wenker SD, Leal MC, Farias MI, Zeng X, Pitossi FJ. Cell therapy for Parkinson’s disease: Functional role of the host immune response on survival and differentiation of dopaminergic neuroblasts. Brain Res. 1638(Pt A):15-29 (2016). doi: 10.1016/j.brainres.2015.06.054. PubMed Review
Murta V, Farias MI, Pitossi FJ, Ferrari CC. Chronic systemic IL-1beta exacerbates central neuroinflammation independently of the blood-brain barrier integrity. J Neuroimmunol. 278: 30-43 (2015). doi: 10.1016/j.jneuroim.2014.11.023. PubMed